PAOX anticorps (AA 260-340)

N° du produit ABIN8123848

Cet anticorps anti-PAOX Polyclonal Lapin (ABIN8123848) détecte spécifiquement PAOX dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Souris, Humain et Rat.

Aperçu rapide pour PAOX anticorps (AA 260-340) (ABIN8123848)

Antigène: PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAOX est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PAOX anticorps

Épitope: AA 260-340

Fonction: PAOX Antibody

Specificité: PAOX Polyclonal Antibody detects endogenous levels of PAOX protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from PAOX . at AA range: 260-340

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PAOX

Antigène: PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

Autre désignation: PAOX

Sujet:

Synonyms: PAOX, PAO, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidase

Background: catalytic activity:N(1),N(12)-diacetylspermine + O(2) + H(2)O = N(1)-acetylspermidine + 3-acetamidobutanal + H(2)O(2).,catalytic activity:N(1)-acetylspermidine + O(2) + H(2)O = putrescine + 3-acetamidopropanal + H(2)O(2).,catalytic activity:N(1)-acetylspermine + O(2) + H(2)O = spermidine + 3-acetamidopropanal + H(2)O(2).,cofactor:Binds 1 FAD per subunit.,function:Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.,induction:By polyamine analogs.,miscellaneous:Oxidizes N(1)-acetylated polyamines on the exo-side of their N(4)-amino groups. Plant PAO oxidizes spermine on the endo-side of the N(4)-nitrogen.,pathway:Amine and polyamine metabolism, spermine metabolism.,similarity:Belongs to the flavin monoamine oxidase family.,subunit:Monomer.,tissue specificity:Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues.,

Gene Name: PAOX

Protein Name: Peroxisomal N(1)-acetyl-spermine/spermidine oxidase

ID gène: 196743

UniProt: Q6QHF9