PHC3 anticorps (AA 720-800)

N° du produit ABIN8123853

L’anticorps anti-PHC3 Polyclonal Lapin est utilisé pour la détection de PHC3 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour PHC3 anticorps (AA 720-800) (ABIN8123853)

Antigène: PHC3 (Polyhomeotic Homolog 3 (PHC3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHC3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PHC3 anticorps

Épitope: AA 720-800

Fonction: PHC3 Antibody

Specificité: PHC3 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 720-800

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PHC3

Antigène: PHC3 (Polyhomeotic Homolog 3 (PHC3))

Autre désignation: PHC3

Sujet:

Background: function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FCS-type zinc finger.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110, BMI1/PCGF4, CBX2/M33, CBX4/PC2, CBX8/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2/RING2.,

Gene Name: PHC3 EDR3 PH3

Protein Name: Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3)

ID gène: 80012

UniProt: Q8NDX5