PTGIS anticorps
Aperçu rapide pour PTGIS anticorps (ABIN8124006)
Antigène
Voir toutes PTGIS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- PGI2 synthase Antibody
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Specificité
- PGI2 synthase Polyclonal Antibody detects endogenous levels of PGI2 synthase protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the C-terminal region of human PGI2 synthase.
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Isotype
- IgG
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Indications d'application
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
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Autre désignation
- PGI2 synthase
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Sujet
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Synonyms: PTGIS, CYP8, CYP8A1, Prostacyclin synthase, Prostaglandin I2 synthase
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008],
Gene Name: PTGIS
Protein Name: Prostacyclin synthase
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ID gène
- 5740
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UniProt
- Q16647
Antigène
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