Proteasome alpha3 (AA 190-270) anticorps

N° du produit ABIN8124041

Cet anticorps Lapin Polyclonal détecte spécifiquement Proteasome alpha3 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Proteasome alpha3 (AA 190-270) anticorps (ABIN8124041)

Antigène: Proteasome alpha3

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit

Épitope: AA 190-270

Fonction: Proteasome α3 Antibody

Specificité: This antibody detects endogenous levels of Human,Mouse,Rat Proteasome α3

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Proteasome alpha3 AA range: 190-270

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détail du antigène

Antigène: Proteasome alpha3

Sujet:

Synonyms: Proteasome subunit alpha type-3 (EC 3.4.25.1, Macropain subunit C8, Multicatalytic endopeptidase complex subunit C8, Proteasome component C8)

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Gene Name: PSMA3 HC8 PSC8

Protein Name: Proteasome α3

ID gène: 5684

UniProt: P25788