PDP anticorps (AA 180-260)
Aperçu rapide pour PDP anticorps (AA 180-260) (ABIN8124180)
Antigène
Voir toutes PDP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 180-260
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Fonction
- PDP1 Antibody
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Specificité
- PDP1 Polyclonal Antibody detects endogenous levels of protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from human protein . at AA range: 180-260
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Isotype
- IgG
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Indications d'application
- WB 1:500-2000 ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- PDP (Pyruvate Dehydrogenase Phosphatase (PDP))
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Autre désignation
- PDP1
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Sujet
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Background: Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported, one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzy
Gene Name: PDP1 PDP PPM2C
Protein Name: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Protein phosphatase 2C) (Pyruvate dehydrogenase phosphatase catalytic subunit 1) (PDPC 1)
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ID gène
- 54704
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UniProt
- Q9P0J1
Antigène
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