RPS6 anticorps (pSer240, pSer244)

N° du produit ABIN8124409

Cet anticorps anti-RPS6 Monoclonal Lapin (Clone AB1610) (ABIN8124409) détecte spécifiquement RPS6 dans WB, IHC, ELISA, IF et IP. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RPS6 anticorps (pSer240, pSer244) (ABIN8124409)

Antigène: RPS6 (Ribosomal Protein S6 (RPS6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RPS6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB1610

Détail du produit anti-RPS6 anticorps

Épitope: pSer240, pSer244

Fonction: RPS6 (Phospho Ser240/Ser244) Rabbit mAb

Specificité: The antibody detects endogenous levels of RPS6 protein only when phosphorylated at Ser240 and Ser244. The antibody does not cross-react with RPS6 phosphorylated at other sites.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:2000-1:10000 | IHC, 1:1000-1:4000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur RPS6

Antigène: RPS6 (Ribosomal Protein S6 (RPS6))

Autre désignation: RPS6

Sujet:

Synonyms: RPS6, OK/SW-cl. 2, 40S ribosomal protein S6, Phosphoprotein NP33

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed

Gene Name: RPS6

Protein Name: RPS6 (Phospho Ser240/Ser244)

ID gène: 6194

UniProt: P62753

Pathways: Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly