RPLP2 anticorps (AA 170-250)

N° du produit ABIN8124428

Cet anticorps Lapin Polyclonal détecte spécifiquement RPLP2 dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour RPLP2 anticorps (AA 170-250) (ABIN8124428)

Antigène: RPLP2 (Ribosomal Protein, Large, P2 (RPLP2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPLP2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-RPLP2 anticorps

Épitope: AA 170-250

Fonction: AntibodyP2 Antibody

Specificité: PABP2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 170-250

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur RPLP2

Antigène: RPLP2 (Ribosomal Protein, Large, P2 (RPLP2))

Autre désignation: P2

Sujet:

Background: This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq, Dec 2010],

Gene Name: PABPN1 PAB2 PABP2

Protein Name: Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)

ID gène: 8106

UniProt: Q86U42