SMAD5 anticorps (pSer463, Ser465)

N° du produit ABIN8124746

Cet anticorps Lapin Monoclonal détecte spécifiquement SMAD5 dans WB, IHC, ELISA, IF et IP. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour SMAD5 anticorps (pSer463, Ser465) (ABIN8124746)

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SMAD5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB1609

Détail du produit anti-SMAD5 anticorps

Épitope: pSer463, Ser465

Fonction: SMAD5 (Phospho Ser463/Ser465) Rabbit mAb

Specificité: The antibody detects endogenous levels of SMAD5 protein only when phosphorylated at Ser463 and Ser465. The antibody does not cross-react with SMAD5 phosphorylated at other sites.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur SMAD5

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Autre désignation: SMAD5

Sujet:

Synonyms: SMAD5, MADH5, Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, JV5-1, SMAD family member 5, SMAD 5, Smad5, hSmad5

Background: The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],

Gene Name: SMAD5

Protein Name: SMAD5 (Phospho Ser463/Ser465)

ID gène: 4090

UniProt: Q99717