Smad1/9 anticorps (AA 400-465)

N° du produit ABIN8124750

L’anticorps anti-Smad1/9 Monoclonal Souris est utilisé pour la détection de Smad1/9 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour Smad1/9 anticorps (AA 400-465) (ABIN8124750)

Antigène: Smad1/9

Reactivité: Humain, Souris, Rat, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Smad1/9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: AB2458

Détail du produit anti-Smad1/9 anticorps

Épitope: AA 400-465

Fonction: Smad1/9 mouse mAb

Specificité: This antibody detects endogenous levels of Smad1/9 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 400 - 465 of the human Smad1/9 protein.

Isotype: IgG

Information d'application

Indications d'application: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Smad1/9

Antigène: Smad1/9

Sujet:

Synonyms: Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1 (SMAD 1, Smad1, hSMAD1) , Transforming growth factor-beta-signaling protein 1 (BSP-1) , SMAD1, BSP1, MADH1, MADR1, Mothers against decapentaplegic homolog 9, MAD homolog 9, Mothers against DPP homolog 9, Madh6, SMAD family member 9 (SMAD 9, Smad9) , SMAD9, MADH6, MADH9, SMAD8

Background: SMAD family member 1 (SMAD1) Homo sapiens The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs) , which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med

Gene Name: SMAD1 SMAD9

Protein Name: Smad1/9

ID gène: 4086

UniProt: Q15797