STARD4 anticorps
Aperçu rapide pour STARD4 anticorps (ABIN8124947)
Antigène
Voir toutes STARD4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- STARD4 Rabbit mAb
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Specificité
- This antibody detects endogenous levels of STARD4 protein.
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Purification
- The antibody was purified by protein A affinity chromatography.
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Immunogène
- Recombinant protein (or fragment).
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Isotype
- IgG
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Indications d'application
- WB, 1:1000-1:5000 | IF, 1:100-1:300 |
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))
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Autre désignation
- STARD4
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Sujet
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Synonyms: STARD4, StAR-related lipid transfer protein 4 , START domain-containing protein 4, StARD4,
Background: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e. g. , SREBP1, MIM 184756) and by liver X receptors (e. g. , LXRA, MIM 602423) . Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617) . STAR is homologous to a family of proteins containing a 200-to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al. , 2002 [PubMed 12011452]) . [supplied by OMIM, Mar 2008]
Gene Name: STARD4
Protein Name: STARD4
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ID gène
- 134429
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UniProt
- Q96DR4
Antigène
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