STIP1 anticorps (AA 250-300)

N° du produit ABIN8124986

Cet anticorps Lapin Polyclonal détecte spécifiquement STIP1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour STIP1 anticorps (AA 250-300) (ABIN8124986)

Antigène: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STIP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-STIP1 anticorps

Épitope: AA 250-300

Fonction: STIP1/HOP Antibody

Specificité: This antibody detects endogenous levels of STIP1/HOP at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human STIP1/HOP AA range: 250-300

Isotype: IgG

Information d'application

Indications d'application: IHC1:50-200 ,WB 1:1000-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur STIP1

Antigène: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Autre désignation: STIP1/HOP

Sujet:

Synonyms: Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)

Background: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A, MIM 140550) and HSP90 (see HSP90AA1, MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],

Gene Name: STIP1

Protein Name: STIP1/HOP

ID gène: 10963

UniProt: P31948