SSRP1 anticorps (AA 209-259)

N° du produit ABIN8125000

Cet anticorps anti-SSRP1 Polyclonal Lapin (ABIN8125000) détecte spécifiquement SSRP1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SSRP1 anticorps (AA 209-259) (ABIN8125000)

Antigène: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSRP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SSRP1 anticorps

Épitope: AA 209-259

Fonction: SSRP1 Antibody

Specificité: This antibody detects endogenous levels of SSRP1 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human SSRP1 AA range: 209-259

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SSRP1

Antigène: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Autre désignation: SSRP1

Sujet:

Background: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008],

Gene Name: SSRP1 FACT80

Protein Name: SSRP1

ID gène: 6749

UniProt: Q08945

Pathways: Chromatin Binding