TFE3 anticorps (AA 100-200)

N° du produit ABIN8125277

Cet anticorps Souris Monoclonal détecte spécifiquement TFE3 dans WB, ELISA, IHC, IF et IP. Il présente une réactivité avec des échantillons de Humain, Souris et Boeuf (Vache).

Aperçu rapide pour TFE3 anticorps (AA 100-200) (ABIN8125277)

Antigène: TFE3 (Transcription Factor E3 (TFE3))

Reactivité: Humain, Souris, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TFE3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB2352

Détail du produit anti-TFE3 anticorps

Épitope: AA 100-200

Fonction: TFE3 mouse mAb

Specificité: This antibody detects endogenous levels of TFE3 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 100 - 200 of the human TFE3 protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | IP, 0. 5 μg-1:4 μg antibody for 200 μg-1:400 μg extracts of whole cells.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur TFE3

Antigène: TFE3 (Transcription Factor E3 (TFE3))

Autre désignation: TFE3

Sujet:

Synonyms: Transcription factor E3, Class E basic helix-loop-helix protein 33 (bHLHe33) , BHLHE33, TFE3

Background: transcription factor binding to IGHM enhancer 3 (TFE3) Homo sapiens This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma) , NONO (non-POU domain containing, octamer-binding) , and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1) , among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],

Gene Name: TFE3

Protein Name: TFE3

ID gène: 7030

UniProt: P19532