TTF1 anticorps

N° du produit ABIN8125285

Cet anticorps anti-TTF1 Monoclonal Lapin (Clone AB2124) (ABIN8125285) détecte spécifiquement TTF1 dans WB, IHC, ELISA, IF et IP. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour TTF1 anticorps (ABIN8125285)

Antigène: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TTF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: AB2124

Détail du produit anti-TTF1 anticorps

Fonction: TTF1 Rabbit mAb

Specificité: This antibody detects endogenous levels of TTF1 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogène: Recombinant protein (or fragment).

Isotype: IgG

Information d'application

Indications d'application: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur TTF1

Antigène: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Autre désignation: TTF1

Sujet:

Synonyms: AV026640, BCH, Benign chorea, BHC, Homeobox protein NK 2 homolog A, Homeobox protein NK-2 homolog A, Homeobox protein Nkx 2. 1, Homeobox protein Nkx-2. 1, Homeobox protein Nkx2. 1, NK 2, NK 2 homolog A, NK2, NK2 homeobox 1, NK2, drosophila, homolog of, A, NK2. 1, Mouse, homolog of, Nkx 2 1, NKX 2. 1, NKX 2A, NKX2 1, Nkx2-1, NKX2. 1, NKX21_HUMAN, NKX2A, T EBP, T/EBP, TEBP, Thyroid nuclear factor 1, Thyroid nuclear factor, Thyroid specific enhancer binding protein, Thyroid transcription factor 1, Tin man, Tinman, TITF 1, TITF1, TTF 1, TTF-1, TTF1

Background: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias &apos, TTF1&apos, with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],

Gene Name: NKX2-1

Protein Name: TTF1

ID gène: 7080

UniProt: P43699

Pathways: Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour