TMPRSS15 anticorps (Cleaved-Ile785, Light Chain)

N° du produit ABIN8125349

Cet anticorps Lapin Polyclonal détecte spécifiquement TMPRSS15 dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TMPRSS15 anticorps (Cleaved-Ile785, Light Chain) (ABIN8125349)

Antigène: TMPRSS15 (Transmembrane Protease, serine 15 (TMPRSS15))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMPRSS15 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-TMPRSS15 anticorps

Épitope: Cleaved-Ile785, Light Chain

Fonction: ENTK (light chain, Cleaved-Ile785) Antibody

Specificité: This antibody detects endogenous levels of Human ENTK (light chain, Cleaved-Ile785, protein was cleaved amino acid sequence between 785-786 )

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human ENTK (light chain, Cleaved-Ile785)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TMPRSS15

Antigène: TMPRSS15 (Transmembrane Protease, serine 15 (TMPRSS15))

Autre désignation: ENTK

Sujet:

Synonyms: Enteropeptidase (EC 3.4.21.9, Enterokinase, Serine protease 7, Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain, Enteropeptidase catalytic light chain]

Background: catalytic activity:Activation of trypsinogen by selective cleavage of 6-Lys-|-Ile-7 bond.,disease:Defects in PRSS7 are a cause of enterokinase deficiency [MIM:226200], a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive.,function:Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.,PTM:The chains are derived from a single precursor that is cleaved by a trypsin-like protease.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 MAM domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 1 SEA domain.,similarity:Contains 1 SRCR domain.,similarity:Contains 2 CUB domains.,similarity:Contains 2 LDL-receptor class A domains.,subunit:Heterodimer of a catalytic (light) chain and a multidomain (heavy) chain linked by a disulfide bond.,tissue specificity:Intestinal brush border.,

Gene Name: TMPRSS15 ENTK PRSS7

Protein Name: ENTK (light chain, Cleaved-Ile785)

ID gène: 5651

UniProt: P98073