STING/TMEM173 anticorps (pSer366)

N° du produit ABIN8125357

Cet anticorps anti-STING/TMEM173 Polyclonal Lapin (ABIN8125357) détecte spécifiquement STING/TMEM173 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour STING/TMEM173 anticorps (pSer366) (ABIN8125357)

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STING/TMEM173 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-STING/TMEM173 anticorps

Épitope: pSer366

Fonction: STING (Phospho Ser366) Antibody

Specificité: This antibody detects endogenous levels of STING (Phospho-Ser366) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human STING (Phospho-Ser366)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur STING/TMEM173

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Autre désignation: STING

Sujet:

Synonyms: Transmembrane protein 173 (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Stimulator of interferon genes protein) (hSTING)

Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],

Gene Name: TMEM173 ERIS MITA STING

Protein Name: STING (Phospho-Ser366)

ID gène: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response