Tropomyosin anticorps (AA 101-150)

N° du produit ABIN8125407

L’anticorps anti-Tropomyosin Polyclonal Lapin est utilisé pour la détection de Tropomyosin dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour Tropomyosin anticorps (AA 101-150) (ABIN8125407)

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tropomyosin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Tropomyosin anticorps

Épitope: AA 101-150

Fonction: Tropomyosin α Antibody

Specificité: Tropomyosin α Polyclonal Antibody detects endogenous levels of Tropomyosin α

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Tropomyosin alpha. at AA range: 101-150

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Tropomyosin

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Autre désignation: Tropomyosin alpha

Sujet:

Synonyms: Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)

Background: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by

Gene Name: TPM1

Protein Name: Tropomyosin α

ID gène: 7168

UniProt: P09493

Pathways: Regulation of Actin Filament Polymerization