Tyrosinase-Related Protein 1 anticorps (Cleaved-Leu80)

N° du produit ABIN8125498

Cet anticorps anti-Tyrosinase-Related Protein 1 Polyclonal Lapin (ABIN8125498) détecte spécifiquement Tyrosinase-Related Protein 1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Tyrosinase-Related Protein 1 anticorps (Cleaved-Leu80) (ABIN8125498)

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Tyrosinase-Related Protein 1 anticorps

Épitope: Cleaved-Leu80

Fonction: CATB (Cleaved-Leu80) Antibody

Specificité: This antibody detects endogenous levels of Human CATB (Cleaved-Leu80, protein was cleaved amino acid sequence between 79-80)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human CATB (Cleaved-Leu80)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Tyrosinase-Related Protein 1

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Autre désignation: CATB

Sujet:

Synonyms: Cathepsin B (EC 3.4.22.1, APP secretase, APPS, Cathepsin B1) [Cleaved into: Cathepsin B light chain, Cathepsin B heavy chain]

Background: catalytic activity:Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.,function:Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.,similarity:Belongs to the peptidase C1 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.,

Gene Name: CTSB CPSB

Protein Name: CATB (Cleaved-Leu80)

ID gène: 1508

UniProt: P07858