TNK1 anticorps (pTyr277)

N° du produit ABIN8125506

L’anticorps anti-TNK1 Polyclonal Lapin est utilisé pour la détection de TNK1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour TNK1 anticorps (pTyr277) (ABIN8125506)

Antigène: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TNK1 anticorps

Épitope: pTyr277

Fonction: TNK1 (Phospho Tyr277) Antibody

Specificité: This antibody detects endogenous levels of Human TNK1 (phospho-Tyr277)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized phosho peptide around human TNK1 (Tyr277)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TNK1

Antigène: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Autre désignation: TNK1

Sujet:

Synonyms: Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)

Background: The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Gene Name: TNK1

Protein Name: TNK1 (Tyr277)

ID gène: 8711

UniProt: Q13470