TNK2 anticorps (pTyr857, pTyr858)

N° du produit ABIN8125507

Cet anticorps anti-TNK2 Polyclonal Lapin (ABIN8125507) détecte spécifiquement TNK2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TNK2 anticorps (pTyr857, pTyr858) (ABIN8125507)

Antigène: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNK2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TNK2 anticorps

Épitope: pTyr857, pTyr858

Fonction: Ack1 (Phospho Tyr857+Tyr858) Antibody

Specificité: This antibody detects endogenous levels of Ack1 (Phospho-Tyr857+Tyr858) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human Ack1 (Phospho-Tyr857+Tyr858)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TNK2

Antigène: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Autre désignation: Ack1

Sujet:

Synonyms: Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)

Background: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008],

Gene Name: TNK2 ACK1

Protein Name: Ack1 (Phospho-Tyr857+Tyr858)

ID gène: 10188

UniProt: Q07912