PROC anticorps (Cleaved-Leu179, Light Chain)

N° du produit ABIN8125721

Cet anticorps Lapin Polyclonal détecte spécifiquement PROC dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PROC anticorps (Cleaved-Leu179, Light Chain) (ABIN8125721)

Antigène: PROC (Vitamin K-dependent protein C (PROC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PROC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-PROC anticorps

Épitope: Cleaved-Leu179, Light Chain

Fonction: PROC (light chain, Cleaved-Leu179) Antibody

Specificité: This antibody detects endogenous levels of Human PROC (light chain, Cleaved-Leu179, protein was cleaved amino acid sequence between 179-180 )

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PROC

Antigène: PROC (Vitamin K-dependent protein C (PROC))

Autre désignation: PROC

Sujet:

Synonyms: Vitamin K-dependent protein C (EC 3.4.21.69, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain, Vitamin K-dependent protein C heavy chain, Activation peptide]

Background: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],

Gene Name: PROC

Protein Name: PROC (light chain, Cleaved-Leu179)

ID gène: 5624

UniProt: P04070