YTHDF2 anticorps
Aperçu rapide pour YTHDF2 anticorps (ABIN8125790)
Antigène
Voir toutes YTHDF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- YTHDF2 Rabbit mAb
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Specificité
- This antibody detects endogenous levels of YTHDF2 protein.
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Purification
- The antibody was purified by protein A affinity chromatography.
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Immunogène
- Recombinant protein (or fragment).
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Isotype
- IgG
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Indications d'application
- WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))
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Autre désignation
- YTHDF2
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Sujet
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Synonyms: YTH domain family protein 2 (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2)
Background: This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene
Gene Name: YTHDF2 HGRG8
Protein Name: YTHDF2
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ID gène
- 51441
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UniProt
- Q9Y5A9
Antigène
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