ZBTB33 anticorps (AA 100-180)

N° du produit ABIN8125797

L’anticorps anti-ZBTB33 Polyclonal Lapin est utilisé pour la détection de ZBTB33 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour ZBTB33 anticorps (AA 100-180) (ABIN8125797)

Antigène: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB33 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ZBTB33 anticorps

Épitope: AA 100-180

Fonction: KAISO Antibody

Specificité: KAISO Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 100-180

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ZBTB33

Antigène: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Autre désignation: KAISO

Sujet:

Background: This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear impor

Gene Name: ZBTB33 KAISO ZNF348

Protein Name: Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33)

ID gène: 10009

UniProt: Q86T24