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LLGL1 + LLGL2 (pSer650), (pSer654) anticorps

L’anticorps Lapin Polyclonal anti- a été validé pour WB, IF (cc), IF (p), ELISA, IHC (fro) et IHC (p). Il convient pour détecter dans des échantillons de Rat.
N° du produit ABIN761981

Aperçu rapide pour LLGL1 + LLGL2 (pSer650), (pSer654) anticorps (ABIN761981)

Antigène

LLGL1 + LLGL2

Reactivité

Rat

Hôte

  • 14
Lapin

Clonalité

  • 14
Polyclonal

Conjugué

  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Inconjugué

Application

Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    pSer650, pSer654

     Réactivité croisée

    Rat

    Homologie

    Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Guinea Pig

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654

    Isotype

    IgG
  • Indications d'application

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Date de péremption

    12 months
  • Antigène

    LLGL1 + LLGL2

    Sub Type

    Cocktail

    Sujet

    Synonyms: LLGL1 + LLGL2 phospho S650 + S654, LLGL1 + LLGL2 phospho Ser650 + Ser654, p-LLGL1 + p-LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650 + Ser654, p-LLGL1/LLGL2 S650 + S654, p-LLGL1/LLGL2 Ser650/654, DLG4, HGL, HUGL, HUGL1, lethal giant larvae homolog 1, lethal giant larvae homolog 2, Lethal2 giant larvae protein homolog 1, Lethal2 giant larvae protein homolog 2, LGL2, LLGL, L2GL1_HUMAN, L2GL2_HUMAN.

    Background: LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

    ID gène

    3996
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