RIN1 anticorps (AA 201-300)

N° du produit ABIN762341

L’anticorps Lapin Polyclonal anti-RIN1 a été validé pour ELISA, IF (cc), IF (p), ICC, IHC (fro) et IHC (p). Il convient pour détecter RIN1 dans des échantillons de Rat.

Aperçu rapide pour RIN1 anticorps (AA 201-300) (ABIN762341)

Antigène: RIN1 (Ras and Rab Interactor 1 (RIN1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIN1 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RIN1 anticorps

Épitope: AA 201-300

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RIN1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RIN1

Antigène: RIN1 (Ras and Rab Interactor 1 (RIN1))

Autre désignation: Rin1

Sujet:

Synonyms: Ras and Rab interactor 1, ras inhibitor 1, ras inhibitor, RIN1_HUMAN, Ras inhibitor JC99, ras inhibitor RIN1, Ras interaction/interference protein 1, RIN 1.

Background: RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.

ID gène: 9610