RIN1 anticorps (AA 201-300) (Biotin)

N° du produit ABIN762343

Cet anticorps Lapin Polyclonal détecte spécifiquement RIN1 dans ELISA, IHC (fro) et IHC (p). Il présente une réactivité envers Rat.

Aperçu rapide pour RIN1 anticorps (AA 201-300) (Biotin) (ABIN762343)

Antigène: RIN1 (Ras and Rab Interactor 1 (RIN1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIN1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RIN1 anticorps (Biotin)

Épitope: AA 201-300

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RIN1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur RIN1

Antigène: RIN1 (Ras and Rab Interactor 1 (RIN1))

Autre désignation: RIN1

Sujet:

Synonyms: Ras and Rab interactor 1, ras inhibitor 1, ras inhibitor, RIN1_HUMAN, Ras inhibitor JC99, ras inhibitor RIN1, Ras interaction/interference protein 1, RIN 1.

Background: RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.

ID gène: 9610