Cet anticorps Souris Monoclonal détecte spécifiquement Lambda-IgLC dans FACS. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.
Flow cytometry: Recommended dilution: 1-4 μg/mL. Extracellular and intracellular staining.
Restrictions
For Research Use only
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Do not freeze.
Stock
4 °C
Stockage commentaire
Store at 2-8°C. Do not freeze.
Tierens, Holte, Warsame, Ikonomou, Wang, Chan, Delabie: "Low levels of monoclonal small B cells in the bone marrow of patients with diffuse large B-cell lymphoma of activated B-cell type but not of germinal center B-cell type." dans: Haematologica, Vol. 95, Issue 8, pp. 1334-41, (2010) (PubMed).
Bahler, Pindzola, Swerdlow: "Splenic marginal zone lymphomas appear to originate from different B cell types." dans: The American journal of pathology, Vol. 161, Issue 1, pp. 81-8, (2002) (PubMed).
Kubagawa, Gathings, Levitt, Kearney, Cooper: "Immunoglobulin isotype expression of normal pre-B cells as determined by immunofluorescence." dans: Journal of clinical immunology, Vol. 2, Issue 4, pp. 264-9, (1983) (PubMed).
Antigène
Lambda-IgLC
(lambda Light Chain (Lambda-IgLC))
Autre désignation
Ig Lambda Light Chain
Sujet
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.,Immunoglobulin lambda, Igl