MAP2 anticorps
Aperçu rapide pour MAP2 anticorps (ABIN781313)
Antigène
Voir toutes MAP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Cytoplasm
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Purification
- Protein G-Sepharose affinity purified.
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Immunogène
- Recombinant fragment of Human MAP2 (C-terminus).
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Isotype
- IgG
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Indications d'application
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- MAP2 (Microtubule-Associated Protein 2 (MAP2))
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Autre désignation
- MAP2
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Sujet
- Microtubule-associated protein 2 (MAP2) is a neuronal phosphoprotein that regulates the structure and stability of microtubules, neuronal morphogenesis, cytoskeleton dynamics and organelle trafficking in axons and dendrites. Phosphorylation of MAP2 modulates its association with the cytoskeleton and is developmentally regulated. Serine 136, threonine 1620 and threonine 1623 of MAP2 are phosphorylated by GSK3 and p44/42 MAP kinases. Phosphorylation at threonine 1620/1623 by GSK3 inhibits MAP2 association with microtubules and microtubule stability.
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Poids moléculaire
- 50kDa
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NCBI Accession
- NM_031846
Antigène
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