TFF1 anticorps (C-Term)

N° du produit ABIN781662

Détail du produit anti-TFF1 anticorps

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Épitope: AA 57-84, C-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TFF1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This Monoclonal antibody detects Human/Porcine Trefoil Factor 1 (TFF1). Antigen Distribution: The antigen has been described in stomach, with highest levels in the upper gastric mucosal cells. Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the. Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system. Detected in urine. Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (Swissprot).

Réactivité croisée (Details): Species reactivity (tested):Human, Pig.

Purification: Affinity Chromatography

Immunogène: Peptide C57 to F84 from Human Trefoil Factor 1. Antigen/Epitope: The antigen is Trefoil Factor 1, the epitope is located in the C-terminal region.

Clone: C-3D5

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 0.5 mL distilled water.

Concentration: 0.2 mg/mL

Buffer: Stock solution contains 0.2 mg/mL IgG, PBS, pH 7.2 with 5 mg/mL BSA as stabilizer and 0.01 % Kathon as a preservative

Agent conservateur: Kathon CG

Précaution d'utilisation: This product contains Kathon CG a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the lyophilized antibody at 2- 8 °C. Following reconstitution, store at -20 °C.

Détails sur TFF1

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Autre désignation: Trefoil Factor 1 / pS2 (TFF1 Produits)

Synonymes: anticorps BCEI, anticorps D21S21, anticorps HP1.A, anticorps HPS2, anticorps pNR-2, anticorps pS2, anticorps Bcei, anticorps PS2, anticorps bcei, anticorps d21s21, anticorps hp1.a, anticorps hps2, anticorps p1, anticorps p1-a, anticorps pnr-2, anticorps ps2, anticorps tff1, anticorps xP1, anticorps xp1-L, anticorps xp1, anticorps TFF1, anticorps Ps2, anticorps trefoil factor 1, anticorps trefoil factor 1 S homeolog, anticorps trefoil factor 1, gene 2 S homeolog, anticorps TFF1, anticorps Tff1, anticorps tff1.S, anticorps tff1.2.S, anticorps LOC100358238

Sujet: Trefoil Factor 1 has been described as a stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. TFF1 may inhibit the growth of calcium oxalate crystals in urine.Synonyms: BCEI, Breast cancer estrogen-inducible protein, PNR-2, Polypeptide P1.A, TFF1

ID gène: 7031

NCBI Accession: NP_003216

UniProt: P04155

Pathways: EGFR Signaling Pathway