Ferritin anticorps

N° du produit ABIN781724

L’anticorps Souris Monoclonal anti-Ferritin a été validé pour EIA et IHC (fro). Il convient pour détecter Ferritin dans des échantillons de Humain.

Aperçu rapide pour Ferritin anticorps (ABIN781724)

Antigène: Ferritin (FE)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ferritin est non-conjugé

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: MAb 44

Détail du produit anti-Ferritin anticorps

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Immunogène: Ferritin from human spleen and liver

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Reconstitute by adding 0.5 mL distilled water.

Buffer: Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 10 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.01 % thimerosal as a preservative

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Détails sur Ferritin

Antigène: Ferritin (FE)

Autre désignation: Ferritin

Sujet: Ferritin consists of a mineral core of hydrated ferric oxide, and a multi-subunit protein shell which englobes the former and assures its solubility in an aqueous environment. It is mainly localized intracellularly in cells of the reticuloendothelial system as well as in liver, spleen and bone marrow. Elevated serum levels are found in patients with iron overload and in other diseases such as pernicious anaemia, chronic inflammations such as rheumatoid arthritis (RA), hepatocellular carcinoma and Hodgkin's disease. Ferritin consists of two components, the apoferritin and the iron core (FeIII - hydroxyphosphate-micelle). The apoferritin is a globular protein built up of 24 subunits that can bind up to 4500 iron atoms. Other non-ferrous metal ions such as Al or Be can also bind to ferritin, which acts partly as a metal ion detoxicant.Synonyms: FTH, FTL, Ferritin H subunit, Ferritin L subunit

Pathways: Transition Metal Ion Homeostasis