CEACAM5 anticorps

N° du produit ABIN782019

Cet anticorps anti-CEACAM5 Monoclonal Souris (Clone B464M) (ABIN782019) détecte spécifiquement CEACAM5 dans IHC (fro) et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CEACAM5 anticorps (ABIN782019)

Antigène: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM5 est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: B464M

Détail du produit anti-CEACAM5 anticorps

Specificité: CEA, epitope specificity group I. Does not crossreact with Human leukocytes in Cytofluorometry.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ion Exchange Chromatography

Immunogène: Human natural tumor-derived purified CEA antigen

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 17.8 mg/mL (OD280nm, E0.1% = 1.4)

Buffer: 10 mM Tris, pH 7.5 containing 0.15 M Sodium Chloride and 0.05 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CEACAM5

Antigène: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Autre désignation: CD66e / CEACAM5

Sujet: CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family (1). The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker (2). CEACAM6 expression is strongly up-regulated already during early stages of adenocarcinoma formation (3). The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.Synonyms: CEA, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Meconium antigen 100

ID gène: 1048

NCBI Accession: NP_004354

UniProt: P06731