Collagen Type I anticorps
Aperçu rapide pour Collagen Type I anticorps (ABIN782308)
Antigène
Voir toutes Collagen Type I (COL1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes Collagen type I (COL1A1).
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
Purification
- Protein A Chromatography
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Immunogène
- Recombinant Human COL1A1
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Isotype
- IgG3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Collagen Type I (COL1) (Collagen, Type I (COL1))
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Autre désignation
- Collagen Type I
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Sujet
- Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.Synonyms: Alpha-1 type I collagen, Alpha-2 type I collagen, COL1A1, COL1A2
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ID gène
- 1277
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NCBI Accession
- NP_000079
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UniProt
- P02452
Antigène
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