L’anticorps Souris Monoclonal anti-LI Cadherin a été validé pour WB, IHC (p) et EIA. Il convient pour détecter LI Cadherin dans des échantillons de Humain.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
PBS, pH 7.2
Conseil sur la manipulation
Avoid freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
Store the antibody (in aliquots) at -20 °C or -80 °C.
Antigène
LI Cadherin
Autre désignation
Cadherin-17
Sujet
The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin beta, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.Synonyms: CDH17, HPT-1, HPT1, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin