BCL11A anticorps (AA 1-89)

N° du produit ABIN782364

Cet anticorps anti-BCL11A est un anticorps Souris Monoclonal détectant BCL11A dans WB, IHC (p) et EIA. Adapté pour Humain.

Aperçu rapide pour BCL11A anticorps (AA 1-89) (ABIN782364)

Antigène: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL11A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 3D9

Détail du produit anti-BCL11A anticorps

Épitope: AA 1-89

Specificité: Recognizes Bcl-11A

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography

Immunogène: BCL11A (NP_060484, 1 a.a. ~ 89 a.a) partial recombinant protein with GST tag.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.

Détails sur BCL11A

Antigène: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Autre désignation: Bcl-11A

Sujet: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.Synonyms: B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BCL11A, COUP-TF-interacting protein 1, CTIP1, EVI9, Ecotropic viral integration site 9 protein homolog, KIAA1809

ID gène: 53335

NCBI Accession: NP_060484

UniProt: Q9H165

Pathways: Regulation of Cell Size