VAMP1 anticorps

N° du produit ABIN782443

Cet anticorps Souris Monoclonal détecte spécifiquement VAMP1 dans WB et IHC (fro). Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Lapin, Porc et Hamster.

Aperçu rapide pour VAMP1 anticorps (ABIN782443)

Antigène: VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Porc, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VAMP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: SP10

Détail du produit anti-VAMP1 anticorps

Specificité: The antibody is specific for the ~16 kDa synaptobrevin protein in Western blots of rat brain lysate.

Réactivité croisée (Details): Species reactivity (tested):Human, Pig, Hamster, Rat, Rabbit, Mouse, and Bovine.
Also reacts to: VAMP2

Purification: Affinity Chromatography.

Immunogène: Synaptic immunoprecipitate (crude) from Human brain.

Isotype: IgM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C.

Détails sur VAMP1

Antigène: VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))

Autre désignation: VAMP-1 / Synaptobrevin-1

Sujet: Synaptobrevin (aka VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al., 2004). Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer's disease (Sze et al., 2000).Synonyms: SYB1, VAMP1, Vesicle-associated membrane protein 1

ID gène: 6843

NCBI Accession: NP_055046

UniProt: P23763