ZBTB5 anticorps (C-Term)

N° du produit ABIN783357

Détail du produit anti-ZBTB5 anticorps

Antigène: ZBTB5 (Zinc Finger and BTB Domain Containing 5 (ZBTB5))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects ZBTB5 at C-term. At least two isoforms of ZBTB5 are known to exist, this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the carboxy terminus of human ZBTB6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur ZBTB5

Antigène: ZBTB5 (Zinc Finger and BTB Domain Containing 5 (ZBTB5))

Autre désignation: ZBTB5 (ZBTB5 Produits)

Synonymes: anticorps 5930421I10, anticorps 9430083K24Rik, anticorps AI646847, anticorps mKIAA0354, anticorps zinc finger and BTB domain containing 5, anticorps ZBTB5, anticorps Zbtb5

Sujet: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.Synonyms: KIAA0354, Zinc finger and BTB domain-containing protein 5

ID gène: 9925

NCBI Accession: NP_055687

UniProt: O15062