ZBTB7A anticorps (N-Term)
Aperçu rapide pour ZBTB7A anticorps (N-Term) (ABIN783361)
Antigène
Voir toutes ZBTB7A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects ZBTB7A at N-term. At least two isoforms of ZBTB7A are known to exist, this antibody will recognize both isoforms. This antibody is predicted not to cross-react with other ZBTB protein family members.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse.
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Purification
- Affinity Chromatography purified via peptide column
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Immunogène
- 16 amino acid peptide near the amino terminus of Human ZBTB7A
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, 0.02 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))
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Autre désignation
- ZBTB7A / Pokemon
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Sujet
- The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB7A, also known as LRF, was initially identified as a potential target of the LAZ-3/BCL-6 oncogene. Later reports demonstrated that it could bind to the wild-type IST (inducer of short transcripts) elements of HIV-1 long terminal repeats (LTRs) and stimulate Tat activity on the HIV-1 LTR. More recently it ZBTB7A has been recognized as a proto-oncogene whose overexpression contributes to malignancy in breast cancer and functions as a co-repressor of the androgen receptor in prostate cancer cells.Synonyms: FBI-1, FBI1, Factor binding IST protein 1, LRF, Leukemia/lymphoma-related factor, POK (POZ and Krueppel) erythroid myeloid ontogenic factor, TIP21, TTF-I-interacting peptide 21, ZBTB7, Zinc finger and BTB domain-containing protein 7A
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ID gène
- 51341
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NCBI Accession
- NP_056982
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UniProt
- O95365
Antigène
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