This antibody detects ZBTB8 at C-term. At least two isoforms of ZBTB8 are known to exist, this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.
Réactivité croisée (Details)
Species reactivity (tested):Human, mouse
Purification
Affinity chromatography purified via peptide column
Immunogène
17 amino acid peptide near the carboxy terminus of human ZBTB8
ZBTB8A
Reactivité: Souris
WB, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 555
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
PBS containing 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Antigène
ZBTB8A
(Zinc Finger and BTB Domain Containing 8A (ZBTB8A))
Autre désignation
ZBTB8
Sujet
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.Synonyms: BOZ-F1, ZBTB8A, Zinc finger and BTB domain-containing protein 8