LRRTM2 anticorps (C-Term)

N° du produit ABIN783381

Cet anticorps anti-LRRTM2 Polyclonal Lapin (ABIN783381) détecte spécifiquement LRRTM2 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour LRRTM2 anticorps (C-Term) (ABIN783381)

Antigène: LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRTM2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-LRRTM2 anticorps

Épitope: C-Term

Specificité: This antibody detects LRRTM2 at C-term. LRRTM2 antibody is predicted to not cross-react with other LRRTM family members.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the carboxy terminus of human LRRTM2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur LRRTM2

Antigène: LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))

Autre désignation: LRRTM2

Sujet: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development.Synonyms: KIAA0416, LRRN2, Leucine-rich repeat neuronal 2 protein, Leucine-rich repeat transmembrane neuronal protein 2

ID gène: 26045

NCBI Accession: NP_056379

UniProt: O43300

Pathways: Synaptic Membrane