ZNF281 anticorps (C-Term)

N° du produit ABIN783429

Détail du produit anti-ZNF281 anticorps

Antigène: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF281 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects ZNF281 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide near the carboxy terminus of human ZFP281

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur ZNF281

Antigène: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Autre désignation: ZNF281 (ZNF281 Produits)

Synonymes: anticorps ZNF281, anticorps zbp-99, anticorps znp-99, anticorps ZBP-99, anticorps ZNP-99, anticorps Znf281, anticorps zinc finger protein 281, anticorps ZNF281, anticorps znf281, anticorps Zfp281

Sujet: ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters. It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression. ZFP281 also interacts with many other other transcription factors, such as Sp1 to repress vimentin gene transcription. ZFP281 has also been shown to control embryonic stem cell pluripotency by direct regulating specific target genes. ZFP281 phyically interacts with the transcription factos POU5F1, Sox2, and NANOG. Gene expression microarray anlysis indicated that some ZFP281 target genes were activated, while others were repressed upon knockdown of ZFP281 expression, showing that ZFP281 plays bifuctinal roles in regulating gene expression in stem cells.Synonyms: GC-box-binding zinc finger protein 1, GZP1, ZBP-99, ZBP99, Zinc finger DNA-binding protein 99, Zinc finger protein 281

ID gène: 23528

NCBI Accession: NP_036614

UniProt: Q9Y2X9

Pathways: Embryonic Body Morphogenesis