2B4 anticorps (C-Term)

N° du produit ABIN783458

Détail du produit anti-2B4 anticorps

Antigène: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 2B4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects CD244 / SLAMF4 at C-term. At least three isoforms of SLAMF4 are known to exist. The antibody is predicted to not cross-react with other SLAM protein family members.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the carboxy terminus of human SLAMF4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur 2B4

Antigène: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Autre désignation: CD244 (CD244 Produits)

Synonymes: anticorps CD244, anticorps 2B4, anticorps NAIL, anticorps NKR2B4, anticorps Nmrk, anticorps SLAMF4, anticorps C9.1, anticorps F730046O15Rik, anticorps Ly90, anticorps CD244 molecule, anticorps CD244 natural killer cell receptor 2B4, anticorps CD244, anticorps Cd244

Sujet: The signaling lymphocyte-activation molecule family member 4 (SLAMF4), also known as 2B4, is an important regulator of Natural Killer (NK) cell activation. It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.Synonyms: NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Natural killer cell receptor 2B4

ID gène: 51744

NCBI Accession: NP_001160135

UniProt: Q9BZW8