KAL1 anticorps (Center)

N° du produit ABIN783480

Détail du produit anti-KAL1 anticorps

Antigène: KAL1 (Kallmann Syndrome 1 Sequence (KAL1))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAL1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Anosmin (Center).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Immunogène: Raised against an 18 amino acid peptide near the center of human Anosmin

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur KAL1

Antigène: KAL1 (Kallmann Syndrome 1 Sequence (KAL1))

Autre désignation: Anosmin-1 (KAL1 Produits)

Synonymes: anticorps ADMLX, anticorps HH1, anticorps HHA, anticorps KAL, anticorps KALIG-1, anticorps KMS, anticorps WFDC19, anticorps KAL1, anticorps hha, anticorps kal, anticorps kms, anticorps admlx, anticorps kalig-1, anticorps anosmin-1a, anticorps kal1.1, anticorps kal1a, anticorps wu:fl91z45, anticorps anosmin 1, anticorps anosmin 1a, anticorps ANOS1, anticorps anos1, anticorps anos1a

Sujet: Mutations in Anosmin-1, an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.Synonyms: ADMLX, Adhesion molecule-like X-linked, KAL, KAL1, KALIG1, Kallmann syndrome protein

ID gène: 3730

NCBI Accession: NP_000207

UniProt: P23352