Translin anticorps (C-Term)

N° du produit ABIN783484

Détail du produit anti-Translin anticorps

Antigène: Translin (TSN)

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Translin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Translin (TSN) at C-term. At least two isoforms of Translin are known to exist, this antibody will detect both.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 20 amino acid peptide near the carboxy terminus of human Translin

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur Translin

Antigène: Translin (TSN)

Abstract: TSN Produits

Sujet: Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.

ID gène: 7247

NCBI Accession: NP_004613

UniProt: Q15631