AP3B2 anticorps (N-Term)

N° du produit ABIN783508

Détail du produit anti-AP3B2 anticorps

Antigène: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AP3B2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody detects AP3 complex subunit beta-2 (N-term).

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: Raised against an 18 amino acid peptide near the amino terminus of human AP3B2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur AP3B2

Antigène: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Autre désignation: AP3 Complex Subunit beta-2 (AP3B2 Produits)

Sujet: The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.Synonyms: AP-3 complex beta-2 subunit, AP3B2, Adapter-related protein complex 3 subunit beta-2, Adaptor protein complex AP-3 beta-2 subunit, Beta 3B Adaptin, Clathrin assembly protein complex 3 beta-2 large chain, Neuron-specific vesicle coat protein beta-NAP, beta-NAP

ID gène: 8120

NCBI Accession: NP_004635

UniProt: Q13367