NUP160 anticorps (C-Term)

N° du produit ABIN783552

Cet anticorps anti-NUP160 Polyclonal Lapin (ABIN783552) détecte spécifiquement NUP160 dans WB, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Souris, Humain et Rat.

Aperçu rapide pour NUP160 anticorps (C-Term) (ABIN783552)

Antigène: NUP160 (Nucleoporin 160kDa (NUP160))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUP160 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-NUP160 anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide from near the carboxy terminus of human NUP160

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur NUP160

Antigène: NUP160 (Nucleoporin 160kDa (NUP160))

Autre désignation: NUP160

Sujet: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment. Multiple isoforms of NUP160 are known to exist.Synonyms: 160 kDa nucleoporin, KIAA0197, NUP120, Nuclear pore complex protein Nup160, Nucleoporin Nup160

ID gène: 23279

NCBI Accession: NP_056046

UniProt: Q12769

Pathways: Protein targeting to Nucleus