STEAP4 anticorps (Center)
Aperçu rapide pour STEAP4 anticorps (Center) (ABIN783554)
Antigène
Voir toutes STEAP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Specificité
- This antibody detects STEAP4 at Center.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 14 amino acid peptide from near the center of human STEAP4
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- STEAP4 (STEAP Family Member 4 (STEAP4))
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Autre désignation
- STEAP4
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Sujet
- The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression. At least two isoforms are known to exist for this protein. This STEAP4 antibody does not cross-react with other STEAP proteins.Synonyms: Metalloreductase STEAP4, STAMP2, STEAP-4, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, TNFAIP9, Tumor necrosis factor, alpha-induced protein 9
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ID gène
- 79689
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NCBI Accession
- NP_078912
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UniProt
- Q687X5
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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