Transportin 3 anticorps (N-Term)

N° du produit ABIN783562

Cet anticorps Lapin Polyclonal détecte spécifiquement Transportin 3 dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Transportin 3 anticorps (N-Term) (ABIN783562)

Antigène: Transportin 3 (TNPO3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transportin 3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Transportin 3 anticorps

Épitope: N-Term

Specificité: This antibody detects Transportin-3 (TNPO3) at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide from near the amino terminus of human TNPO3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur Transportin 3

Antigène: Transportin 3 (TNPO3)

Autre désignation: Transportin-3 (TNPO3)

Sujet: TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins. Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated. More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment. At least three isoforms of TNPO3 are known to exist.Synonyms: IPO12, Imp12, Importin-12, TRN-SR, Transportin-SR

ID gène: 23534

NCBI Accession: NP_001177957

UniProt: Q9Y5L0

Pathways: Protein targeting to Nucleus