TTR anticorps (Center)
Aperçu rapide pour TTR anticorps (Center) (ABIN783574)
Antigène
Voir toutes TTR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Specificité
- This antibody detects Transthyretin / Prealbumin at Center.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 17 amino acid peptide near the center of human Transthyretin
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- TTR (Transthyretin (TTR))
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Autre désignation
- Transthyretin / Prealbumin
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Sujet
- Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson's disease, schizophrenia, and depression.Synonyms: ATTR, PALP, TBPA, TTR
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ID gène
- 7276
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NCBI Accession
- NP_000362
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UniProt
- P02766
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Pathways
- Hormone Transport
Antigène
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