NSMCE2 anticorps (C-Term)

N° du produit ABIN783606

Cet anticorps anti-NSMCE2 Polyclonal Lapin (ABIN783606) détecte spécifiquement NSMCE2 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NSMCE2 anticorps (C-Term) (ABIN783606)

Antigène: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NSMCE2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-NSMCE2 anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat

Purification: Immunoaffinity Chromatography

Immunogène: 15 amino acid peptide near the carboxy terminus of Human MMS21

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur NSMCE2

Antigène: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Autre désignation: NSMCE2

Sujet: MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression, this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.Synonyms: C8orf36, E3 SUMO-protein ligase NSE2, MMS21

ID gène: 286053

NCBI Accession: NP_775956

UniProt: Q96MF7