L’anticorps Lapin Polyclonal anti-IFITM1 a été validé pour WB, IF et EIA. Il convient pour détecter IFITM1 dans des échantillons de Humain, Rat et Souris.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store the antibody (in aliquots) at -20 °C.
Antigène
IFITM1
(Interferon-Induced Transmembrane Protein 1 (IFITM1))
Autre désignation
CD225 / IFITM1
Sujet
IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-g-induced antiproliferation and plays a role in the control of cell growth. IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.Synonyms: IFI17, Interferon-induced protein 17, Interferon-induced transmembrane protein 1, Interferon-inducible protein 9-27, Leu-13 antigen